Regulation of HD-ZIPIII Transcription Factors by Deeply-conserved START Domains

After receiving a Bachelor of Science from the University of Toronto, Aman pursued a PhD in Patricia Springer’s lab at the University of California - Riverside. Using biochemical and genetic analyses, he demonstrated that the LOB DOMAIN genes constitute a new class of plant-specific transcription factors, regulating a variety of developmental processes including brassinosteroid signaling, adaxial-abaxial polarity, and lateral root production. After receiving his PhD, Aman joined Marja Timmermans lab at Cold Spring Harbor Laboratory in NY, who has since moved to the University of Tuebingen in Germany. There he studied the molecular mechanisms that polarize the adaxial-abaxial (or dorsoventral) axis, which drives the production of flat leaf architecture. Finally, in January of 2018, Aman joined the Molecular Genetics department at Ohio State. His lab is interested in the mechanisms that govern complexity and reproducibility, two outcomes which seem in tension yet are both defining features of development.