Lynda Barry has worked as a painter, cartoonist, writer, illustrator, playwright, editor, commentator and teacher and found they are very much alike. The New York Times has described Barry as "among this country’s greatest conjoiners of words and images, known for plumbing all kinds of touchy subjects in cartoons, comic strips and novels, both graphic and illustrated." She earned a degree from Evergreen State College during its early experimental period (1974-78), studying with painter and writing teacher Marilyn Frasca. Frasca’s questions about the nature of images and the role they play in day-to-day living have guided Barry’s work ever since.

In 1979 while pursuing a career as a painter, Barry began drawing a weekly comic strip incorporating stories considered to be incompatible with comics at the time. Stories, as Barry puts it, “that had a lot of trouble in them.” Widely credited with expanding the literary, thematic and emotional range of American comics, Barry’s seminal comic strip, Ernie Pook’s Comeek, ran in alternative newspapers across North America for thirty years.

Barry has authored 21 books, worked as a commentator for NPR, and written a regular monthly feature in Esquire, Mother Jones Magazine, Mademoiselle, and Salon. She created an album-length spoken word collection of stories called The Lynda Barry Experience, and was a frequent guest on the Late Show with David Letterman.  She adapted her first novel, The Good Times are Killing Me, into a long running off-Broadway play, since published by Samuel French and performed throughout North America.  Her book One! Hundred! Demons! was chosen as the Freshman all-read title at Stanford University.  Her novel Cruddy was called “a work of terrible beauty” by the New York Times, and has been translated into French, Italian, German, Catalan and Hebrew. Her newest book, Making Comics, was awarded the 2020 Eisner Award for Best Comics-Related Book + Best Publication Design.