Ali Tamoyal (UHCH) - Chemistry Departmental Seminar

Conventional practices for the treatment of commonly observed medical problems such as chronic wounds and musculoskeletal injuries have shown limited effectiveness. To address this unmet need, micro- and nanoscale technologies are increasingly used. These technologies have merged with advanced materials to enable engineering constructs, which mimic the biochemical, topographical, and physical features of the native tissues. In addition, microfabrication technologies have enabled scientists to mimic the complexity of the native tissues through controlling cell-cell and cell-microenvironment interactions. Along with the advancements in understanding the pathophysiology of hard-to-treat wounds such as diabetic ulcers, new therapies have been devised to overcome the barriers preventing tissue healing and regeneration. During this presentation, I will highlight our research progresses in developing solutions for the treatment of volumetric muscle and bone loss. I will also discuss our research in the area of wound and skin care. The presented microengineered platforms will have broad applications in the fields of tissue engineering, drug delivery, and drug testing.